The exact causes of the disease are not fully understood, but it became well known that chronic atopic dermatitis is a combination of interactions between :

  • Distorted operation of the skin barrier
  • Immunological factors
  • Environmental factors
  • Genetic predisposition
  • Further there are some allergizing agents which affect a flare of the disease such as:
  • Woolen clothes from rough fabrics
  • Plants and pollen
  • Bleach and other chemical agents